Research Administration

Thomas Wells, MD, MBA

Professor of Pediatrics, University of Arkansas for Medical Sciences/College of Medicine/Department of Pediatrics

Phone: (501) 364-1100

Research Overview

In addition to the serving ACHRI as the Medical Director of the Pediatric Clinical Research Unit (PCRU) at Arkansas Children’s Hospital (ACH), Dr. Wells pursues his research interests at ACHRI. He studies blood pressure and treatment for high blood pressure in children. Dr. Wells has conducted over 12 antihypertension studies through ACHRI since 1999 and has worked with most major pharmaceutical firms to develop pediatric trials for antihypertension drugs. Dr. Wells is involved in clinical trials through the NIH-funded Pediatric Pharmacology Research Unit (PPRU) at ACH. The PPRU conducts carefully controlled clinical trials to establish safety and effectiveness of many medications commonly used to treat a variety of childhood illnesses. Dr. Wells served as the Director of the PPRU for 10 years. As well as his commitments to ACHRI, Dr. Wells is the Director of the Office of Clinical Trials and the Director of the Research Support Center at UAMS.

Key Publications

Maples HD, James LP, Stowe CD, Jones DP, Hak EB, Blumer JL, Vogt B, Wilson JT, Kearns GL, Wells TG. Famotidine Disposition in Children and Adolescents with Chronic Renal Insufficiency. J Clin Pharmacol 43:7-14, 2003.

Chien S, Wells TG, Blumer JL, Kearns GL, Bradley JS, Bocchini JA, Natarajan J, Maldonado S, Noel G. Levofloxacin Pharmacokinetics in Children. J Clin Pharmacol 45:153-160, 2005.

Wells TG . Pediatric Antihypertensive Trials. In: Pediatric Hypertension. Portman RJ, Sorof JM, Ingelfinger JR (eds). Humana Press, Inc., Totowa, NJ, pp. 443-455, 2004.

Wells TG , Ilyas M. Antihypertensive Agents. In: Neonatal and Pediatric Pharmacology: Therapeutic Principles in Practice. Yaffe SJ, Aranda JV (eds). Lippincott, Williams & Wilkins, Philadelphia, PA, pp. 678-697, 2005.

To find addional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports.

Research Support

NIH/NICHD: Pediatric Pharmacology Research Unit Network, 2U10 HD31324-11, 1/04-12/08, $1,952,037