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Research OverviewDr. Stine’s investigative interests include treatment of malignant bone tumors and other sarcomas. He is the local Principal investigator for Sarcoma Alliance through Research Collaboration. He seeks to discover new uses of cytokines as anti-neoplastic agents. In addition, he is involved in therapeutic studies of Langerhan's cell histiocytosis and the natural history and treatment studies of hemophilia and other bleeding disorders as well as thrombophilia. Key PublicationsStine KC , Saylors, RL, Saccente, CS, and Becton, DL. Treatment of Deep Vein Thrombosis with Enoxaparin in Pediatric Cancer Patients Receiving Chemotherapy. Clinical and Applied Thrombosis and Hemostasis, in press (Vol 13) 2007. Ullah S, Schmitz ML, Stine KC, Johnson CE, Faulkner SC, Drummond-Webb JJ. Post Cardiopulmonary bypass coagulopathy in a neonate with a family history of von Willebrand Disease. The Journal of Cardiothoracic and Vascular Anesthesia 20(4):576-579, 2006 (August) Bernstein M, Devidas, M, Lafreniere D, Souid A-K, Meyers P, Gebhardt M, Stine K, Nicholas R, Perlman E, Dubowy R, Wainer I, Link M, Goorin A, Grier H. Intensive Therapy with Growth Facotr Support for Patients with Ewing Tumor Metastatic at Diagnosis, POG/CCG Phase II Study 9457: A Report from the Children’s Oncology Group. Journal Clinical Oncology 24:152-159, 2006. Becton D., Dahl GV, Ravindranath Y, Chang MN, Gehm FG, Raimondi SC, Head DR, Stine KC, Sikic BI, Arceci RJ, Weinstein H. Randomized use of cyclosporine A (CSA) to modulate p-glycoprotein in children with AML in remission: Pediatric Oncology Group Study 9421. Blood 107:1315-1324, 2006. Stine KC, Saylors RL, Saccente S, McClain KL, Becton DL. Efficacy of continuous infusion 2-CDA (Cladribine) in pediatric patients with Langerhan’s Cell Histiocytosis. Pediatric Blood and Cancer, 2004; 43(1):81-84 (July). *To find additional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports. Research SupportMCHB: Region VI Comprehensive Hemophilia Program (AR site/subcontract with UT) CDC: Prevention of the Complications of Hemophilia Through Hemophilia Treatment Centers (subcontract with UT)
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