Research Overview

Dr. Schnackenberg is an Instructor within the Department of Pediatrics and a researcher in the ACHRI Lung Cell Biology Laboratory. Dr. Schnackenberg’s research focuses on the role of cell-cell adhesion proteins and how these proteins are modulated during proper wound closure. He uses a combination of primary airway epithelial cell cultures and isolated lung tissue in his research. Pathological problems in wound closure add to the morbidity of respiratory diseases such as asthma, where airways are often partially denuded of epithelia and chronic wound repair results in airway remodeling. Dr. Schnackenberg also employs a mouse model of allergic asthma to study how these mechanisms may be altered in a disease state.

Key Publications*

Schnackenberg, B.J., Jones, S.M., Pate, C., Shank, B., Sessions, L., Pittman, L.M., Cornett, L.E., and Kurten, R.C. (2006). The beta-agonist isoproterenol attenuates EGF-stimulated wound closure in human airway epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiology. 290 (3): L485-L491.

Kurten, R.C., Chowdhury, P., Sanders, R.C., Pittman, L.M., Sessions, L.W., Chambers, T.C., Lyle, C.S., Schnackenberg, B.J., and Jones, S.M. (2005). Coordinating epidermal growth factor induced motility promotes efficient wound closure. Am. J. Physiol. Cell Physiol. 288 (1): C109-C121.

*To find additional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports.